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Volume 8
Main Index

Issue 1


Chemistry and Structure of Mitomycin C
Calvin L. Stevens, K. Grant Taylor, Morton E. Munk, W. S. Marshall, Klaus Noll, G. D. Shah, L. G. Shah, and K. Uzu
pp 1 - 10; DOI:
10.1021/jm00325a001
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Potential Anticancer Agents. II. The Synthesis of Some Nitrogen Mustard Containing Sulfones and Thiosulfinates
Allen F. Hirsch, Claude Piantadosi, and J. Logan Irvin
pp 10 - 14; DOI:
10.1021/jm00325a002
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Enzyme-Alterable Alkylating Agents. VII. The Design of Short-Lived Mustards
Samuel Sass, Charles E. Williamson, Stanley P. Kramer, Louis E. Goodman, Adolph Ulfohn, Arnold M. Seligman, and Benjamin Witten
pp 14 - 17; DOI:
10.1021/jm00325a003
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Structure Studies on Vancomycin
Frederick J. Marshall
pp 18 - 22; DOI:
10.1021/jm00325a004
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The Chemistry of Cephalosporin Antibiotics. III. Acylation of Cephalosporadesates
Earle Van Heyningen
pp 22 - 25; DOI:
10.1021/jm00325a005
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Syntheses with 5-Nitro-2-furonitrile
W. R. Sherman and Anne Von Esch
pp 25 - 28; DOI:
10.1021/jm00325a006
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Potential Antiradiation Drugs. I. Amide, Hydroxamic Acid, and Hydrazine Derivatives of Mercapto Acids. Amino Thioacids
Edward R. Atkinson, G. Richard Handrick, Robert J. Bruni, and Felix E. Granchelli
pp 29 - 33; DOI:
10.1021/jm00325a007
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Enzyme Inhibitors. VI. Studies on the Bulk Tolerance of Adenosine Deaminase for 6-Substituted Amino-9-(3-hydroxypropyl)purines
Howard J. Schaeffer and Robert Vince
pp 33 - 35; DOI:
10.1021/jm00325a008
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Analogs of Tetrahydrofolic Acid. XVII.1,2 On the Mode of Binding of the p-Aminobenzoyl Moiety of N-(2-Amino-4-hydroxy-6-methyl-6-pyrimidylpropyl)-p-aminobenzoyl- L-glutamic Acid to Dihydrofolic Reductase
B. R. Baker and Johannes H. Jordaan
pp 35 - 41; DOI:
10.1021/jm00325a009
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Synthesis of Fatty Acids with Smooth Muscle Stimulant Activity
E. Crundwell, M. A. Pinnegar, and W. Templeton
pp 41 - 45; DOI:
10.1021/jm00325a010
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Hypocholesterolemic Agents. V.1a Isomeric Azacholesterols1b
R. E. Counsell, P. D. Klimstra, L. N. Nysted, and R. E. Ranney
pp 45 - 48; DOI:
10.1021/jm00325a011
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Anabolic Agents. A-Ring Conjugated Enone Androstane Derivatives
P. D. Klimstra and R. E. Counsell
pp 48 - 52; DOI:
10.1021/jm00325a012
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Mammalian Antifertility Agents. I. Derivatives of 2,3-Diphenylindenes
Daniel Lednicer, John C. Babcock, Paul E. Marlatt, Stanley C. Lyster, and Gordon W. Duncan
pp 52 - 57; DOI:
10.1021/jm00325a013
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Studies in Alkyl-Oxygen Heterolysis. Some 4-Alkoxypiperidines Related to Reversed Esters of Pethidine
A. F. Casy and N. A. Armstrong
pp 57 - 61; DOI:
10.1021/jm00325a014
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Spiranes. VII. Neuroleptics Derived from Azaspiranes
Charles H. Grogan, Charles F. Geschickter, Meier E. Freed, and Leonard M. Rice
pp 62 - 73; DOI:
10.1021/jm00325a015
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Derivatives of Morphanthridine
L. H. Werner, S. Ricca, E. Mohacsi, A. Rossi, and V. P. Arya
pp 74 - 80; DOI:
10.1021/jm00325a016
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The Synthesis and Pharmacology of Some Substituted 1,3-Benzodioxoles and 1,4-Benzodioxans
M. W. Baines, D. B. Cobb, R. J. Eden, R. Fielden, J. N. Gardner, A. M. Roe, W. Tertiuk, and G. L. Willey
pp 81 - 90; DOI:
10.1021/jm00325a017
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Diuretics. 6-Substituted 3-Ketoalkyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides and Related Anils, Oximes, and Hydrazones
Jerry E. Robertson, Donald A. Dusterhoft, and Thomas F. Mitchell
pp 90 - 95; DOI:
10.1021/jm00325a018
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Behavioral Stimulants. 4-Oxazolidinones
John B. Bicking, Sara F. Kwong, Michael H. Fisher, and William H. Nicholson
pp 95 - 100; DOI:
10.1021/jm00325a019
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Behavioral and Neuropharmacological Actions of N-Aralkylhydroxylamines and Their O-Methyl Ethers
F. Benington, R. D. Morin, and L. C. Clark
pp 100 - 104; DOI:
10.1021/jm00325a020
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Synthesis and Pharmacological Study of New Piperazine Derivatives. II. Phenethylpiperazines
R. Ratouis, J. R. Boissier, and C. Dumont
pp 104 - 107; DOI:
10.1021/jm00325a021
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p-Amino-N-[2-(substituted amino)ethyl]benzamides. Potential Antifibrillatory Drugs
Per Thyrum and Allan R. Day
pp 107 - 111; DOI:
10.1021/jm00325a022
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Pyridoxine Chemistry. VI. Homologs of Pyridoxol and of 5-Pyridoxic Acid
W. Korytnyk
pp 112 - 115; DOI:
10.1021/jm00325a023
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Pyridoxine Chemistry. VII.1a Some Modifications in the 4-Position of Pyridoxol1b
R. P. Singh and W. Korytnyk
pp 116 - 117; DOI:
10.1021/jm00325a024
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Substitution in the Hydantoin Ring. I. N-3-Aminomethyl Derivatives
Meldrum B. Winstead, Donald E. Barr, Coleman R. Hamel, D. James Renn, Harriet I. Parker, and Richard M. Neumann
pp 117 - 120; DOI:
10.1021/jm00325a025
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Substitution in the Hydantoin Ring. II. N-3-Acetic Acid Derivatives
Meldrum B. Winstead and Coleman R. Hamel
pp 120 - 122; DOI:
10.1021/jm00325a026
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N,N-Diethyl-2,2-dimethylpropane-1,3-diamine
Morris Freifelder and Yew Hay Ng
pp 122 - 123; DOI:
10.1021/jm00325a027
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Derivatives of Morphine. IV.1 14-Hydroxymorphine and 14-Hydroxydihydromorphine
Ulrich Weiss and Sol J. Daum
pp 123 - 125; DOI:
10.1021/jm00325a028
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1,2,3,4-Tetrahydroisoquinoline Derivatives with Antihypertensive Properties
Wilhelm Wenner
pp 125 - 126; DOI:
10.1021/jm00325a029
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N-Ethoxy-4-ethylamino-3-methyl-2-phenyl-2-propionoxy-1-α-pyridylbutane. An Analog of the Analgesic Propoxyphene
Randolph T. Major, Konrad Fitzi, and Hans-Jürgen Hess
pp 127 - 129; DOI:
10.1021/jm00325a030
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Synthesis and Pharmacological Study of Pyridazines. I. Alkoxypyridazines
Peter Coad, Raylene Adams Coad, Barry Dubinsky, Joseph P. Buckley, and William Kinnard
pp 129 - 131; DOI:
10.1021/jm00325a031
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Novel Oral Hypoglycemic Agents. I. Hexahydroindeno[1,2-c]pyrroles and Indanamines
Samir Chandra Lahiri and Balai Pathak
pp 131 - 133; DOI:
10.1021/jm00325a032
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17α-Methylandrostane-3α,17β-diol
K. R. Bharucha and F. M. Martin
pp 133 - 136; DOI:
10.1021/jm00325a033
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Benzo[b]thiophene Derivatives. V. Mannich Bases With Antimicrobial Activity
E. Campaigne, E. D. Weinberg, G. Carlson, and E. S. Neiss
pp 136 - 137; DOI:
10.1021/jm00325a034
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4-(Alkoxystyryl)quinolines
C. T. Bahner, H. Kinder, and T. Rigdon
pp 137 - 138; DOI:
10.1021/jm00325a035
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The Purification of Aminopterin
Ti Li Loo
pp 139 - 139; DOI:
10.1021/jm00325a036
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Some 3,4,5-Trimethoxy-Substituted Benzamides
S. K. Sogani and P. C. Dandiya
pp 139 - 140; DOI:
10.1021/jm00325a037
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1-(2-Deoxy-D-glucopyranosyl)-5-fluorocytosine
George J. Durr
pp 140 - 141; DOI:
10.1021/jm00325a038
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Some Bis(3-nitro- and 3-amino-4-alkoxy- and -4-aryloxyphenyl) Sulfones
William F. Hart and Martin E. McGreal
pp 141 - 142; DOI:
10.1021/jm00325a039
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A Convenient Synthesis of Aminotryptamines Analogous to Serotonin
S. P. Hiremath and S. Siddappa
pp 142 - 143; DOI:
10.1021/jm00325a040
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New Derivatives of 9-Amino-1,2,3,4-tetrahydroacridine
W. P. Brian and B. L. Souther
pp 143 - 144; DOI:
10.1021/jm00325a041
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7- and 12-(o-Halophenyl)benz[a]anthracenes
Frank A. Vingiello, Leo Ojakaar, and Rosalie Kelsey
pp 144 - 144; DOI:
10.1021/jm00325a042
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Survey of Chemical Notation Systems
Frederick Y. Wiselogle
pp 145 - 145; DOI:
10.1021/jm00325a043
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Advances in Chemotherapy. Volume I.
Alfred Burger
pp 145 - 145; DOI:
10.1021/jm00325a044
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The Background to Chemotherapy of Virus Diseases
Alfred Burger
pp 145 - 145; DOI:
10.1021/jm00325a045
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Research Progress in Organic--Biological and Medicinal Chemistry. Volume I.
Alfred Burger
pp 146 - 146; DOI:
10.1021/jm00325a046
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Progress in Drug Research. Volume 7.
Alfred Burger
pp 146 - 146; DOI:
10.1021/jm00325a047
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Experimental Chemotherapy. Volume III. Chemotherapy of Bacterial Infections. Part II. Chemotherapy of Fungal, Rickettsial, and Viral Infections
Alfred Burger
pp 146 - 146; DOI:
10.1021/jm00325a048
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Issue 2


Stereochemical Studies on Medicinal Agents. II. Absolute Configuration of (-)-Phenampromide
Philip S. Portoghese
pp 147 - 150; DOI:
10.1021/jm00326a001
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Substituent Constants for Aliphatic Functions Obtained from Partition Coefficients
Junkichi Iwasa, Toshio Fujita, and Corwin Hansch
pp 150 - 153; DOI:
10.1021/jm00326a002
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The Formation of O-Methylated Catechols by Microsomal Hydroxylation of Phenols and Subsequent Enzymatic Catechol O-Methylation.
John Daly, Joseph K. Inscoe, and Julius Axelrod
pp 153 - 157; DOI:
10.1021/jm00326a003
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Excretion, Distribution, and Metabolism of Doxapram Hydrochloride
Robert B. Bruce, J. E. Pitts, Franklin Pinchbeck, and Jack Newman
pp 157 - 164; DOI:
10.1021/jm00326a004
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A Simple Test Tube Arrangement for Screening Fibrinolytic Activity of Synthetic Organic Compounds
Kurt N. von Kaulla
pp 164 - 166; DOI:
10.1021/jm00326a005
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A Study of Comparative Chemical and Biological Activities of Alkylating Agents
T. J. Bardos, N. Datta-Gupta, P. Hebborn, and D. J. Triggle
pp 167 - 174; DOI:
10.1021/jm00326a006
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The Chemistry of Cephalosporins. IV. Acetoxyl Replacements with Xanthates and Dithiocarbamates
Earle Van Heyningen and Carter N. Brown
pp 174 - 181; DOI:
10.1021/jm00326a007
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Synthesis and Antitumor Activity of 9-Substituted Nitrogen Mustard Derivatives of 6-Alkylthiopurines
Darrell E. O'Brien, James D. Westover, Roland K. Robins, and C. C. Cheng
pp 182 - 187; DOI:
10.1021/jm00326a008
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Nitrogen Mustards Derived from 3,4-Dihydro-2,4-dioxo-1(2H)-pyrimidinepropionic and -butyric Acids
Abelardo P. Martinez, William W. Lee, and Leon Goodman
pp 187 - 189; DOI:
10.1021/jm00326a009
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Purine N-Oxides. XV. The Synthesis of 6-Mercaptopurine 3-N-Oxide. Its Chemotherapeutic Possibilities
George Bosworth Brown, Gershon Levin, Sarah Murphy, Alex Sele, H. Christine Reilly, George S. Tarnowski, Franz A. Schmid, Morris N. Teller, and C. Chester Stock
pp 190 - 195; DOI:
10.1021/jm00326a010
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Pyrimidinecarbamates and Thiolcarbamates Derived from Amino- and Oxopyrimidines. II
Elizabeth Dyer and Henry Richmond
pp 195 - 200; DOI:
10.1021/jm00326a011
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Acyltryptamines. IV.1 Azepino[5,4,3-cd]indoles
Maximilian von Strandtmann, Marvin P. Cohen, and John Shavel
pp 200 - 204; DOI:
10.1021/jm00326a012
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1-p-Chlorobenzyl-5-methylindole-3-acetic Acid. Some 2-Substituted Derivatives
Edward Walton, Charles H. Stammer, Ruth F. Nutt, Susan R. Jenkins, and Frederick W. Holly
pp 204 - 208; DOI:
10.1021/jm00326a013
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Thio Analogs of Carisoprodol (N-Isopropyl-2-methyl-2-propyl-1,3-propanediol Dicarbamate)
M. A. Leaffer, W. A. Skinner, and B. J. Ludwig
pp 208 - 212; DOI:
10.1021/jm00326a014
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Adrenal Cortical Inhibitors and Potent Synthetic Estrogens
W. L. Bencze, L. I. Barsky, W. P. Sopchak, A. A. Renzi, N. Howie, and J. J. Chart
pp 213 - 214; DOI:
10.1021/jm00326a015
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The Modification of 11β-Hydroxy-11α-methyl-5β-pregnane-3,20-dione Dioxime under Acidic Conditions
Donald R. Buhler, Louis C. Schroeter, and W. J. Wechter
pp 215 - 219; DOI:
10.1021/jm00326a016
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DL-1-(1-Arylalkyl)imidazole-5-carboxylate Esters. A Novel Type of Hypnotic Agents
Erik F. Godefroi, Paul A. J. Janssen, Cyriel A. M. Van der Eycken, Albert H. M. T. Van Heertum, and Carlos J. E. Niemegeers
pp 220 - 223; DOI:
10.1021/jm00326a017
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Hypocholesteremic Agents. III.1 Basic Carbinols and Related Compounds
James H. Short, Ursula Biermacher, Daniel A. Dunnigan, G. Frederick Lambert, Donald L. Martin, Carl W. Nordeen, and Howard B. Wright
pp 223 - 230; DOI:
10.1021/jm00326a018
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The Synthesis of Phencyclidine and Other 1-Arylcyclohexylamines
V Harold Maddox, Erik F. Godefroi, and Robert F. Parcell
pp 230 - 235; DOI:
10.1021/jm00326a019
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Structures Related to Morphine. XXVIII.1 Alternative Syntheses of α- and β-2,9-Dimethyl-2′-hydroxy-5-propyl-6,7-benzomorphan
Colin F. Chignell, J. Harrison Ager, and Everette L. May
pp 235 - 238; DOI:
10.1021/jm00326a020
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The Chemistry and Pharmacology of a Series of Cycloalkanespiro-5′-hydantoins
W. Oldfield and C. H. Cashin
pp 239 - 249; DOI:
10.1021/jm00326a021
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Synthetic Antigonadotropins. III
H. H. Fox, J. T. Gibas, H. L. Lee, and A. Boris
pp 250 - 251; DOI:
10.1021/jm00326a022
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Synthesis of 6- and 7-Bis(2-chloroethyl)amino-DL-tryptophan
Leon Goodman, Roland R. Spencer, Giovanni Casini, Osborne P. Crews, and Elmer J. Reist
pp 251 - 252; DOI:
10.1021/jm00326a023
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Carcinogenic Activity of 2-N,N-Dimethylamino-5-phenylazopyridine
Ellis V. Brown, Andrew F. Smetana, and Ali A. Hamdan
pp 252 - 253; DOI:
10.1021/jm00326a024
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Some 5-Fluoropyrimidines
G. J. Durr
pp 253 - 255; DOI:
10.1021/jm00326a025
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New 1-Aminomethylbenzocyclobutenes
Joseph A. Skorcz and Jerry E. Robertson
pp 255 - 257; DOI:
10.1021/jm00326a026
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A New Group of Antifibrillants. N-(ω-Aminoalkyl)phthalimides
Kálmán Hideg and H. Olga Hankovszky
pp 257 - 259; DOI:
10.1021/jm00326a027
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The Synthesis of Ethyl α-(p-Chlorophenyl)-6,7-dimethoxy-2-methyl- 1,2,3,4-tetrahydro-1-isoquinolinepropionate
Glenn C. Morrison and John Shavel
pp 259 - 260; DOI:
10.1021/jm00326a028
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Synthesis and Biological Activities of Certain Short-Chain Mono- and Bisquaternary Ammonium Compounds
Walter L. Graef, Joseph G. Cannon, and Joseph P. Buckley
pp 260 - 263; DOI:
10.1021/jm00326a029
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1,3,2-Diazaphosphorinane 2-Oxides. II.1 Synthesis of Some 1,3-Bis(aralkyl)-2-(N-arylamino)-1,3,2-diazaphosphorinane 2-Oxides2
John H. Billman and John L. Meisenheimer
pp 264 - 265; DOI:
10.1021/jm00326a030
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Hexahydro-11H-pyrrolo[2,1-α]-β-carbolines and Tetrahydro-13H-isoindolo[1,2-α]-β-carbolines
S. Wawzonek and J. D. Nordstrom
pp 265 - 267; DOI:
10.1021/jm00326a031
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A Carbocyclic Analog of Glyceraldehyde Dimer
James G. Murphy
pp 267 - 268; DOI:
10.1021/jm00326a032
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The Preparation and Some Biological Properties of 17α-Ethyl-17β-methyl-Δ4,13-gonadien-3-one
R. Y. Kirdani and R. I. Dorfman
pp 268 - 269; DOI:
10.1021/jm00326a033
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Hydroxy-, Nitro-, Amino-, and Methoxy-4-(4-dimethylaminostyryl)quinolines
Carl Tabb Bahner, David Brotherton, William H. Chapman, William Longmire, H. Bernie Orr, Lydia Moore Rives, Emma Brown Senter, and Warren Yee
pp 269 - 271; DOI:
10.1021/jm00326a034
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Synthesis and Pharmacological Study of New Piperazine Derivatives. III. Phenoxyalkylpiperazines
R. Ratouis, J. R. Boissier, and C. Dumont
pp 271 - 273; DOI:
10.1021/jm00326a035
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Synthesis of Tripeptides of 1-Aminocyclopentane-1-carboxylic Acid
J. Friedrich Diehl and David O. Bowen
pp 274 - 274; DOI:
10.1021/jm00326a036
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An Improved Synthesis of Oxotremorine
Alan Bebbington and Derek Shakeshaft
pp 274 - 275; DOI:
10.1021/jm00326a037
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Perchloric Acid in the Preparation of 2′,3′-Isopropylidene 6-Thioinosine
John A. Zderic, John G. Moffatt, Don Kau, Koert Gerzon, and William E. Fitzgibbon
pp 275 - 275; DOI:
10.1021/jm00326a038
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Synthesis of Some Amino Acid Thiol Esters
Robert A. Ray and Robert B. Johnston
pp 275 - 276; DOI:
10.1021/jm00326a039
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Advances in Drug Research. Volume 1.
Alfred Burger
pp 277 - 277; DOI:
10.1021/jm00326a040
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Molecular Modification in Drug Design.
Alfred Burger
pp 277 - 277; DOI:
10.1021/jm00326a041
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Science Citation Index. Volume 1, 1964.
Wilhelm Moll
pp 277 - 278; DOI:
10.1021/jm00326a042
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Pharmaceutical Microbiology.
Charles J. Paget
pp 278 - 278; DOI:
10.1021/jm00326a043
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Handbook of Chemistry and Physics.
Alfred Burger
pp 278 - 278; DOI:
10.1021/jm00326a044
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CORRECTION

pp 278 - 278; DOI:
10.1021/jm00326a045
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Issue 3


Structure-Activity Relationships in the Field of Antibacterial Steroid Acids
Josef Fried, Gerald W. Krakower, David Rosenthal, and Harold Basch
pp 279 - 282; DOI:
10.1021/jm00327a001
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Analogs of Tetrahydrofolic Acid. XVIII.1,2 On the Mode of Binding of Some 6-Aryl- and 6-Aralkylpyrimidines to Folic Reductase
B. R. Baker, Howard S. Shapiro, and William C. Werkheiser
pp 283 - 287; DOI:
10.1021/jm00327a002
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Amino Acid Analogs of Tryptamine Antagonists of Serotonin
Frederick Leonard and Walter Tschannen
pp 287 - 290; DOI:
10.1021/jm00327a003
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2-Amino-3-methylthiobutyric Acid, an Isoleucine Antagonist
Tommy J. McCord, Drusilla Cook Howell, Don L. Tharp, and Alvie L. Davis
pp 290 - 292; DOI:
10.1021/jm00327a004
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Synthesis of Some Pyrimidine Amino Acids by the Rhodanine Method and Tests vs. the Ehrlich Ascites Carcinoma
Vilhjalmur G. Skulason, Claude Piantadosi, Benjamin F. Zamberana, and J. Logan Irvin
pp 292 - 295; DOI:
10.1021/jm00327a005
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Synthesis and Structure-Activity Relationships of Some Aminopyridines, Imidazopyridines, and Triazolopyridines
M. M. Vohra, S. N. Pradhan, P. C. Jain, S. K. Chatterjee, and Nitya Anand
pp 296 - 304; DOI:
10.1021/jm00327a006
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Derivatives of Imidazole. I. Synthesis and Reactions of Imidazo[1,2-α]pyridines with Analgesic, Antiinflammatory, Antipyretic, and Anticonvulsant Activity
Luigi Almirante, Luigi Polo, Alfonso Mugnaini, Ercolina Provinciali, Pierluigi Rugarli, Adriana Biancotti, Afro Gamba, and Walter Murmann
pp 305 - 312; DOI:
10.1021/jm00327a007
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3-Alkyl-3-phenylpiperidine Derivatives as Analgesics. II
Hiroshi Kugita, Toyonari Oine, Hirozumi Inoue, and Goro Hayashi
pp 313 - 316; DOI:
10.1021/jm00327a008
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Analgetics Based on the Pyrrolidine Ring. IV
J. F. Cavalla, D. C. Bishop, R. A. Selway, N. E. Webb, C. V. Winder, and M. Welford
pp 316 - 326; DOI:
10.1021/jm00327a009
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Bicyclic Homologs of Piperazine. VII.1 Synthesis and Analgesic Activity of 3-Aralkenyl-8-propionyl-3,8-diazabicyclo[3.2.1]octanes
Giorgio Cignarella, Emilio Occelli, and Emilio Testa
pp 326 - 331; DOI:
10.1021/jm00327a010
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N,N′-Disubstituted Compounds with Diverse Biological Activities
Robert P. Mull, Carl Tannenbaum, Mary R. Dapero, Marcel Bernier, William Yost, and George DeStevens
pp 332 - 338; DOI:
10.1021/jm00327a011
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Yohimbane Derivatives. II. The Synthesis and Psychopharmacological Properties of Yohimbane Derivatives with Halogen Substitutents in Ring E
Maximilian von Strandtmann, George Bobowski, and John Shavel
pp 338 - 341; DOI:
10.1021/jm00327a012
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Triptycene Derivatives as Medicinal Agents
Edmund C. Kornfeld, Pam Barney, John Blankley, and William Faul
pp 342 - 347; DOI:
10.1021/jm00327a013
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Derivatives of Fluorene. XIX.1,2 9-o-Chlorocinnamylidenefluorene and Related Compounds
T. Lloyd Fletcher, Moses J. Namkung, John R. Dice, and Sandra K. Schaefer
pp 347 - 350; DOI:
10.1021/jm00327a014
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5-Methylpyrazole-3-carboxylic Acid. The Potent Hypoglycemic Metabolite of 3,5-Dimethylpyrazole in the Rat
David L. Smith, Arlington A. Forist, and William E. Dulin
pp 350 - 353; DOI:
10.1021/jm00327a015
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The Effects of Ring-Methoxyl Groups on Biological Deamination of Phenethylamines
Leland C. Clark, Frederick Benington, and Richard D. Morin
pp 353 - 355; DOI:
10.1021/jm00327a016
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Some Cardiovascular Effects of a Series of Aryloxyalkylamines. I
J. Augstein, W. C. Austin, R. J. Boscott, S. M. Green, and C. R. Worthing
pp 356 - 367; DOI:
10.1021/jm00327a017
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Ultraviolet Absorption Spectra and Apparent Acidic Dissociation Constants of Some Phenolic Amines
Thomas Kappe and Marvin D. Armstrong
pp 368 - 374; DOI:
10.1021/jm00327a018
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Antifungal Activity of a Series of Substituted [(α-Nitroalkyl)benzylthio]alkylamines
Robert C. Tweit, R. D. Muir, Seth Mizuba, and Webster R. Crowley
pp 374 - 377; DOI:
10.1021/jm00327a019
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Phosphorylated Benzenesulfonamides as Animal Systemic Insecticides
Frank A. Wagner, Ronald W. Baer, and Gerald Berkelhammer
pp 377 - 383; DOI:
10.1021/jm00327a020
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Spiro-3-oxiranyl-5α-androstan-17β-ols
H. G. Lehmann, O. Engelfried, and R. Wiechert
pp 383 - 384; DOI:
10.1021/jm00327a021
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Structures Related to Morphine. XXIX.1 Further Experiments on the Stereo-Controlled Reduction of 9-Methylene-6,7-benzomorphans
Colin F. Chignell and Everette L. May
pp 385 - 386; DOI:
10.1021/jm00327a022
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Synthesis of 17-Acetoxy-6-chloro-21-fluoropregna-4,6-diene-3,20-dione, a Highly Active Oral Progestin
Robert F. R. Church and Martin J. Weiss
pp 386 - 387; DOI:
10.1021/jm00327a023
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2H-1,3,2-Oxazaphosphorine Derivatives
Carl Tabb Bahner, Hughlan W. Pope, and David Brotherton
pp 387 - 388; DOI:
10.1021/jm00327a024
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2-Methacryloxytropones. Intermediates for the Synthesis of Biologically Active Polymers
Robert J. Cornell and L. Guy Donaruma
pp 388 - 390; DOI:
10.1021/jm00327a025
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Improved Synthesis of Oxotremorine
John L. Archibald
pp 390 - 390; DOI:
10.1021/jm00327a026
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Benzylidene Derivatives of Indene and Cyclopentadiene
Carl Tabb Bahner, Harold Kinder, David Brotherton, John Spiggle, and Lee Gutman
pp 390 - 392; DOI:
10.1021/jm00327a027
PDF
Nuclear Magnetic Resonance Spectra of Phenothiazines. Chemical Shift Data
J. Cymerman Craig, D. E. Green, S. K. Roy, L. H. Piette, and Kay O. Loeffler
pp 392 - 395; DOI:
10.1021/jm00327a028
PDF
The Synthesis, Proof of Structure, and Biological Activity of Some Monosubstituted Aminoguanidines
J. Augstein, S. M. Green, A. R. Katritzky, and A. M. Monro
pp 395 - 397; DOI:
10.1021/jm00327a029
PDF
Styrylquinoline Analogs from Heterocyclic Carboxaldehydes
Carl Tabb Bahner, Harold Kinder, and Lee Gutman
pp 397 - 398; DOI:
10.1021/jm00327a030
PDF
α- and γ-Glutamyl Derivatives of Aminobenzoic Acids
Rodney F. Lloyd, Charles G. Skinner, William Shive, and R. John Stedman
pp 398 - 400; DOI:
10.1021/jm00327a031
PDF
Synthesis of N,N-Bis(2-haloethyl) Aliphatic Amides
Carlos H. Gaozza
pp 400 - 401; DOI:
10.1021/jm00327a032
PDF
Agents Affecting Lipid Metabolism. XVI. The Synthesis of Analogs of trans-1,4-Bis(2-chlorobenzylaminomethyl)cyclohexane
Leslie G. Humber
pp 401 - 404; DOI:
10.1021/jm00327a033
PDF
A Convenient Synthesis of 5-Hydroxy-2-methyltryptophan
Frederick Leonard and Walter Tschannen
pp 404 - 405; DOI:
10.1021/jm00327a034
PDF
The Synthesis of Disalicyl Alcohols
Jose Philip and John A. McLean
pp 405 - 405; DOI:
10.1021/jm00327a035
PDF
Aromatic Fluorine Compounds. XIII. Substituted N-Phenylglycine Ethyl Esters and Hydrazides
G. C. Finger, D. R. Dickerson, L. D. Starr, and D. E. Orlopp
pp 405 - 407; DOI:
10.1021/jm00327a036
PDF
Green Medicine. The Search for Plants that Heal.
Alfred Burger
pp 407 - 408; DOI:
10.1021/jm00327a037
PDF
Infrared Absorption Spectroscopy.
A. R. Patel
pp 408 - 408; DOI:
10.1021/jm00327a038
PDF
Application of NMR Spectroscopy in Organic Chemistry.
Robert A. Pages
pp 408 - 408; DOI:
10.1021/jm00327a039
PDF
Medical Pharmacology.
Daniel T. Watts
pp 408 - 408; DOI:
10.1021/jm00327a040
PDF

Issue 4


The Preparation and Pharmacology of Some 3-Desoxyestratrienes. Lipid-Shifting and Estrogenic Effects
Arthur H. Goldkamp, Willard M. Hoehn, Richard A. Mikulec, Ehard F. Nutting, and Donald L. Cook
pp 409 - 414; DOI:
10.1021/jm00328a001
PDF
Synthetic Antigonadotropins. IV. Bromotriphenylethylenes
H. H. Fox, J. T. Gibas, H. L. Lee, and A. Boris
pp 415 - 416; DOI:
10.1021/jm00328a002
PDF
Action of Some Steroids on the Central Nervous System of the Mouse. I. Synthetic Methods
J. D. Cocker, J. Elks, P. J. May, F. A. Nice, G. H. Phillipps, and W. F. Wall
pp 417 - 425; DOI:
10.1021/jm00328a003
PDF
Action of Some Steroids on the Central Nervous System of the Mouse. II. Pharmacology
R. M. Atkinson, B. Davis, M. A. Pratt, Helen M. Sharpe, and E. G. Tomich
pp 426 - 432; DOI:
10.1021/jm00328a004
PDF
Synthesis of cis- and trans-2-Phenoxycyclopropylamines and Related Compounds
Jacob Finkelstein, Elliot Chiang, and John Lee
pp 432 - 439; DOI:
10.1021/jm00328a005
PDF
Amine Oxidases. XXI. A Rapid Method for the Determination of the Activity of Monoamine Oxidase and Monoamine Oxidase Inhibitors
Verena Zeller, Gollamudi Ramachander, and E. Albert Zeller
pp 440 - 443; DOI:
10.1021/jm00328a006
PDF
Synthesis of Compounds with Potential Psychotomimetic Activity. III1,2a
Robert J. Adamski and Joseph G. Cannon
pp 444 - 446; DOI:
10.1021/jm00328a007
PDF
Hydroxylamine Chemistry. V. Aralkoxyguanidines
D. G. Martin, E. L. Schumann, W. Weldkamp, and H. Keasling
pp 446 - 456; DOI:
10.1021/jm00328a008
PDF
Hydroxylamine Chemistry. V. Aralkoxyguanidines
D. G. Martin, E. L. Schumann, W. Veldkamp, and H. Keasling
pp 456 - 459; DOI:
10.1021/jm00328a009
PDF
Synthesis and Preliminary Pharmacology of Some 1-Methylindoles
Robert G. Taborsky, Peter Delvigs, Irvine H. Page, and Neville Crawford
pp 460 - 466; DOI:
10.1021/jm00328a010
PDF
Stereochemistry of d-3,4-Dimethyl-2-phenylmorpholine (Phendimetrazine)
D. Dvornik and G. Schilling
pp 466 - 469; DOI:
10.1021/jm00328a011
PDF
The Synthesis of Thyromimetic Substances and Potential Inhibitors of Thyroxine
Charles M. Buess, Tullio Giudici, Norman Kharasch, William King, D. David Lawson, and N. N. Saha
pp 469 - 474; DOI:
10.1021/jm00328a012
PDF
Hypocholesterolemic Agents. Thyroalkanols
W. J. Wechter, W. A. Phillips, and F. Kagan
pp 474 - 478; DOI:
10.1021/jm00328a013
PDF
The Synthesis of Tenuazonic and Congeneric Tetramic Acids
Stanton A. Harris, Linda V. Fisher, and Karl Folkers
pp 478 - 482; DOI:
10.1021/jm00328a014
PDF
Antitumor, Cytotoxic, and Antibacterial Activities of Tenuazonic Acid and Congeneric Tetramic Acids
C. O. Gitterman
pp 483 - 486; DOI:
10.1021/jm00328a015
PDF
Polynucleotides. III.1 Synthesis of (3′→5′)-Linked Diribonucleoside Phosphates Containing 3- and 5-Methyluracil
Roosevelt Thedford, Maurice H. Fleysher, and Ross H. Hall
pp 486 - 491; DOI:
10.1021/jm00328a016
PDF
Derivatives of Fluorene. XXI. New Halogenofluorenes. II.1a Further Potential Antitumor Agents
Hsi-Lung Pan and T. Lloyd Fletcher
pp 491 - 497; DOI:
10.1021/jm00328a017
PDF
Hexahydropyrimidines. V.1 A Study of 2-Substituted 1,3-Bis(α-cyanobenzyl)-hexahydropyrimidines and 2-Substituted 1,3-Bis(α-cyano-p-methoxybenzyl)-hexahydropyrimidines as Prospective Antitumor Agents2
John H. Billman and M. Sami Khan
pp 498 - 499; DOI:
10.1021/jm00328a018
PDF
Synthesis of Methyl DL-3-Phthalimido-5-oxo-6-diazohexanoate
Loren L. Braun and Roger M. Layton
pp 500 - 502; DOI:
10.1021/jm00328a019
PDF
Enzyme Inhibitors. VIII. Studies on the Mode of Binding of Some 6-Substituted 9-(Hydroxyalkyl)purines to Adenosine Deaminase
Howard J. Schaeffer, David Vogel, and Robert Vince
pp 502 - 506; DOI:
10.1021/jm00328a020
PDF
Enzyme Inhibitors. IX. Hydrophobic Interactions of Some 9-Alkyladenines with Adenosine Deaminase
Howard J. Schaeffer and David Vogel
pp 507 - 509; DOI:
10.1021/jm00328a021
PDF
Glutamic Acid Analogs. The Synthesis of 3-Alkylgutamic Acids and 4-Alkylpyroglutamic Acids
Yoon C. Kim and George H. Cocolas
pp 509 - 513; DOI:
10.1021/jm00328a022
PDF
The Metabolite of 3′,5′-Dichloro-4-amino-4-deoxy-N10-methylpteroylglutamic Acid (Dichloromethotrexate)
Ti Li Loo and Richard H. Adamson
pp 513 - 515; DOI:
10.1021/jm00328a023
PDF
Synthesis and Pharmacological Action of 3-Amino-2,1-benzisothiazoles
Robert F. Meyer, Betty L. Cummings, Paul Bass, and H. O. J. Collier
pp 515 - 519; DOI:
10.1021/jm00328a024
PDF
The Metabolism of N-Alkyl-4-bromobenzenesulfonamides in the Mouse. Correlation with Anticonvulsant Activity
David L. Smith, Hugh H. Keasling, and Arlington A. Forist
pp 520 - 524; DOI:
10.1021/jm00328a025
PDF
exo-3-Chloro-endo-6-cyano-2-norbornanone O-(Methylcarbamoyl)oxime. A New Type of Methylcarbamate with Acaricidal Activity
Linwood K. Payne, Harry A. Stansbury, and Mathias H. J. Weiden
pp 525 - 528; DOI:
10.1021/jm00328a026
PDF
Chemical Structure and Pharmacological Activity of Glycine Derivatives. Influence of Disubstitution of the Amine Function of Glycine Esters and Hydrazides
Richard Rips, Christian Derappe, and Pierre Magnin
pp 529 - 531; DOI:
10.1021/jm00328a027
PDF
3-Piperonylsydnone. A New Type of Antimalarial Agent
Wayne H. Nyberg and C. C. Cheng
pp 531 - 533; DOI:
10.1021/jm00328a028
PDF
Thyroxine Analogs. XV.1 Synthesis and Antigoitrogenic Activity of the 3′-t-Butyl Analog of 3,5,3′-Triiodo-L-thyronine and Its O-Methyl Ether
Eugene C. Jorgensen and James A. W. Reid
pp 533 - 536; DOI:
10.1021/jm00328a029
PDF
17-Chloroethynylated Steroids. III. The Synthesis of 17α-Chloroethynyl-5,7,9-estratrien-17β-ol-3-one
John Hannah and John H. Fried
pp 536 - 537; DOI:
10.1021/jm00328a030
PDF
A-Nor Oxa Steroids
Seymour D. Levine
pp 537 - 539; DOI:
10.1021/jm00328a031
PDF
Synthesis of Potential Antidiabetic Agents. 1-p-Tolylsulfonyl-2-benzimidazolinones and 1-p-Tolylsulfonyl-2-benzimidazolinethiones
John B. Wright
pp 539 - 540; DOI:
10.1021/jm00328a032
PDF
Hexahydropyrimidines. VI. Some 2-{4-[N,N-Bis(2-chloroethyl)amino]aryl}- 1,3-bis(aralkyl)hexahydropyrimidines
John H. Billman and John L. Meisenheimer
pp 540 - 540; DOI:
10.1021/jm00328a033
PDF
N4-(2-Bromoethyl)-N4-ethylsulfanilamide, a Monofunctional Nitrogen Mustard with Antitumor Action
P. Hebborn and D. J. Triggle
pp 541 - 542; DOI:
10.1021/jm00328a034
PDF
Basic Ethers of Guaiacol and Thymol with a Polyoxyethylenic Chain and Their Main Pharmacological Activities. New Antitussives
M. Carissimi, A. Cattaneo, R. D'Ambrosio, V. De Pascale, E. Grumelli, E. Milla, and F. Ravenna
pp 542 - 545; DOI:
10.1021/jm00328a035
PDF
Insect Chemosterilants. II.1 N-Carbamoylaziridines
Alexej B. Bořkovec and Charles W. Woods
pp 545 - 547; DOI:
10.1021/jm00328a036
PDF
Cytotoxicity of Cardiac Principles
R. B. Kelly, Edward G. Daniels, and L. Bayard Spaulding
pp 547 - 548; DOI:
10.1021/jm00328a037
PDF
The Relationship between Structure and Anticonvulsant Activity in a Series of Benzenesulfonamides
H. H. Keasling, E. L. Schumann, and W. Veldkamp
pp 548 - 550; DOI:
10.1021/jm00328a038
PDF
Some 2,3,6-Trisubstituted Quinazolones
K. Kishor, R. C. Arora, and Surendra S. Parmar
pp 550 - 551; DOI:
10.1021/jm00328a039
PDF
Derivatives of Fluorene. XX.1a,b Fluorofluorenes. V. New Difluoro-2-acetamidofluorenes for the Study of Carcinogenic Mechanisms
Moses J. Namkung, T. Lloyd Fletcher, and William H. Wetzel
pp 551 - 554; DOI:
10.1021/jm00328a040
PDF
The Synthesis of DL-p-(Hydroxymethyl)phenylalanine
G. W. E. Plaut
pp 554 - 555; DOI:
10.1021/jm00328a041
PDF
Coupling Reactions in the Synthesis of Amitriptyline
R. D. Hoffsommer, D. Taub, and N. L. Wendler
pp 555 - 556; DOI:
10.1021/jm00328a042
PDF
Psychopharmacological Agents. Volume I.
Alfred Burger
pp 556 - 556; DOI:
10.1021/jm00328a043
PDF

Issue 5


N-Allylnorapomorphine
Jerome F. Hensiak, Joseph G. Cannon, and Allan M. Burkman
pp 557 - 559; DOI:
10.1021/jm00329a001
PDF
Constitution and Analgetic Activity of a New Product in the Benzomorphan Synthesis
Bhuwan C. Joshi, Everette L. May, H. M. Fales, J. W. Daly, and A. E. Jacobson
pp 559 - 563; DOI:
10.1021/jm00329a002
PDF
Structures Related to Morphine. XXXI.1 2′-Substituted Benzomorphans
Arthur E. Jacobson and Everette L. May
pp 563 - 566; DOI:
10.1021/jm00329a003
PDF
Analgesics. Some Substituted 2,3-Dihydro-4-quinolones
M. S. Atwal, L. Bauer, S. N. Dixit, J. E. Gearien, and R. W. Morris
pp 566 - 571; DOI:
10.1021/jm00329a004
PDF
Chemistry and Pharmacology of Some Esters Derived from Basic Alcohols
F. P. Doyle, M. D. Mehta, R. Ward, J. Bainbridge, and D. M. Brown
pp 571 - 576; DOI:
10.1021/jm00329a005
PDF
Cardiac Glycosides and Aglycones by Synthesis and Microbiological Conversion
Francis G. Henderson and K. K. Chen
pp 577 - 579; DOI:
10.1021/jm00329a006
PDF
The Adamantyl Group in Medicinal Agents. II. Anabolic Steroid 17β-Adamantoates
Richard T. Rapala, Russell J. Kraay, and Koert Gerzon
pp 580 - 583; DOI:
10.1021/jm00329a007
PDF
Synthesis of α-(p-Aminophenyl)- and α-(p-Chlorophenyl)-β-arylpropionitriles by Catalytic Reduction of Stilbenenitriles
Gordon N. Walker
pp 583 - 588; DOI:
10.1021/jm00329a008
PDF
Synthesis and Pharmacological Evaluation of α,α-Disubstituted Derivatives of Phenylacetonitrile and 1-Naphthylacetonitrile
Silvano Casadio, Gianfranco Pala, Elda Crescenzi, Tiberio Bruzzese, Ernesta Marazzi-Uberti, and Germano Coppi
pp 589 - 593; DOI:
10.1021/jm00329a009
PDF
Synthesis and Pharmacological Evaluation of α,α-Disubstituted Derivatives of Phenylacetamide and 1-Naphthylacetamide
Silvano Casadio, Gianfranco Pala, Tiberio Bruzzese, Elda Crescenzi, Ernesta Marazzi-Uberti, and Germano Coppi
pp 594 - 598; DOI:
10.1021/jm00329a010
PDF
Nonsteroidal Antiinflammatory Agents. Some Arylacetic Acids
G. J. Durant, G. M. Smith, R. G. W. Spickett, and E. Szarvasi
pp 598 - 603; DOI:
10.1021/jm00329a011
PDF
Silicon-Substituted Medicinal Agents. Silacarbamates Related to Meprobamate
Ralph J. Fessenden and Marvin D. Coon
pp 604 - 608; DOI:
10.1021/jm00329a012
PDF
A New Concept on the Mode of Interaction of Narcotic Analgesics with Receptors
Philip S. Portoghese
pp 609 - 616; DOI:
10.1021/jm00329a013
PDF
Stereochemical Factors Related to the Potency of Anticholinergic Psychotomimetic Drugs
Norman W. Gabel and Leo G. Abood
pp 616 - 619; DOI:
10.1021/jm00329a014
PDF
Compounds Affecting the Central Nervous System. I. 4-Piperidones and Related Compounds
C. R. Ganellin and R. G. W. Spickett
pp 619 - 625; DOI:
10.1021/jm00329a015
PDF
Synthesis of New 3-(Pyridylmethylene)-, 3-(Pyridylmethyl)-, 3-(Piperidylmethyl)-, and 3-(β-Alkylaminoethyl)-2-indolinones. The Reduction of Isoindogenides, Nitro Compounds, and Pyridines in a Series of 2-Indolinones
Gordon N. Walker, Ronald T. Smith, and Barbara N. Weaver
pp 626 - 637; DOI:
10.1021/jm00329a016
PDF
Pyrazine Diuretics. I. N-Amidino-3-amino-6-halopyrazinecarboxamides
John B. Bicking, James W. Mason, Otto W. Woltersdorf, James H. Jones, Sara F. Kwong, Charles M. Robb, and Edward J. Cragoe
pp 638 - 642; DOI:
10.1021/jm00329a017
PDF
Physiologically Active Compounds. VI. Cyclic Amino Thiolesters of Substituted Chloroacetic, Benzilic, and Glycolic Acids
Calvin A. Buehler, Shelby F. Thames, L. G. Abood, and J. H. Biel
pp 643 - 647; DOI:
10.1021/jm00329a018
PDF
Effect of Organic Compounds on Reproductive Processes. I. Alkylating Agents from Octamethylenediamine and Various Xylylenediamines
W. A. Skinner, H. C. Tong, T. E. Shellenberger, and G. W. Newell
pp 647 - 650; DOI:
10.1021/jm00329a019
PDF
Some Amino and Ammonio Nitrogen Mustard Analogs
Charles C. Price, Guglielmo Kabas, and Isao Nakata
pp 650 - 655; DOI:
10.1021/jm00329a020
PDF
Diazo, Bromo, and Mesyloxy Ketones as Biological Alkylating Agents
T. Nogrady, T. W. Doyle, and L. Morris
pp 656 - 659; DOI:
10.1021/jm00329a021
PDF
3′-Deoxynucleosides. II. Purine 3′-Deoxynucleosides
Edward Walton, Frederick W. Holly, George E. Boxer, Ruth F. Nutt, and Susan R. Jenkins
pp 659 - 663; DOI:
10.1021/jm00329a022
PDF
Relation of Structure to Activity of Purine 3′-Deoxynucleosides in KB Cell and Chick Embryo Fibroblast Cell Cultures
C. O. Gitterman, R. W. Burg, G. E. Boxer, D. Meltz, and J. Hitt
pp 664 - 667; DOI:
10.1021/jm00329a023
PDF
The Synthesis and Properties of 6-Mercaptomethylpurine and Derivatives
Alfredo Giner-Sorolla and Aaron Bendich
pp 667 - 672; DOI:
10.1021/jm00329a024
PDF
Structural Studies of an Active Principle from Croton tiglium L.
Eugene R. Arroyo and J. Holcomb
pp 672 - 675; DOI:
10.1021/jm00329a025
PDF
Antiviral Chemotherapy. I. The Activity of Pyridine and Quinoline Derivatives against Neurovaccinia in Mice
D. H. Jones, R. Slack, S. Squires, and K. R. H. Wooldridge
pp 676 - 680; DOI:
10.1021/jm00329a026
PDF
Antiviral Chemotherapy. II. Structure-Activity Relationships in a Series of Isothiazolealdehyde and Ketone Thiosemicarbazones
M. P. L. Caton, D. H. Jones, R. Slack, S. Squires, and K. R. H. Wooldridge
pp 680 - 683; DOI:
10.1021/jm00329a027
PDF
Aminooxy Derivatives. IV. Antimicrobial Activity of Some O-Ethers of 4,6-Diamino-1,2-dihydro-1-hydroxy-2-substituted 1,3,5-Triazines
P. Mamalis, L. Jeffries, S. A. Price, M. J. Rix, and D. J. Outred
pp 684 - 691; DOI:
10.1021/jm00329a028
PDF
New Sulfonamides
J. M. Loynes, H. F. Ridley, and R. G. W. Spickett
pp 691 - 694; DOI:
10.1021/jm00329a029
PDF
Structures Related to Morphine. XXX.1 N-Hexyl- and 5-Butyl-, -Amyl-, and -Hexyl-6,7-benzomorphans
Bhuwan C. Joshi, Colin F. Chignell, and Everette L. May
pp 694 - 696; DOI:
10.1021/jm00329a030
PDF
Structures Related to Morphine. XXXII.1 α- and β-2,9-Dimethyl-5-propyl-6,7-benzomorphan from 3-Methyl-4-propylpyridine
Bhuwan C. Joshi and Everette L. May
pp 696 - 697; DOI:
10.1021/jm00329a031
PDF
1-(3-Phenylpropyl)-2-methyl-6,7-methylenedioxy-8-methoxy-1,2,3,4- tetrahydroisoquinoline, a Pharmacologically Active Narcotine Derivative
Arthur E. Jacobson
pp 697 - 698; DOI:
10.1021/jm00329a032
PDF
Structure-Activity Relationships in Antiinflammatory and Analgesic Compounds Chemically Related to α-Isopropyl-α-(2-dimethylaminoethyl)-1-naphthylacetamide
G. Pala, S. Casadio, T. Bruzzese, E. Crescenzi, and E. Marazzi-Uberti
pp 698 - 700; DOI:
10.1021/jm00329a033
PDF
9-(2-Aminoethyl)-2,3-dihydro-1H-pyrrolo[1,2-a]-indoles, New Tryptamine Analogs
William A. Remers and Martin J. Weiss
pp 700 - 702; DOI:
10.1021/jm00329a034
PDF
Isomeric Benzyldiaminodihydrotriazines
Howard Newman and Edward L. Moon
pp 702 - 704; DOI:
10.1021/jm00329a035
PDF
Spiranes. IX. Amides of 3,9-Dicarboxy-2,4,8,10-tetraoxaspiro[5.5]undecane
Leonard M. Rice and Charles H. Grogan
pp 704 - 705; DOI:
10.1021/jm00329a036
PDF
The Structure-Activity Relationship in Penicillins
Corwin Hansch and Edna W. Deutsch
pp 705 - 706; DOI:
10.1021/jm00329a037
PDF
Dihydrazides, a New Class of Anthelmintics
Raymond Cavier and Richard Rips
pp 706 - 708; DOI:
10.1021/jm00329a038
PDF
Deaza Analogs of 6-Mercaptopurine
John A. Montgomery and Kathleen Hewson
pp 708 - 710; DOI:
10.1021/jm00329a039
PDF
Enzyme Inhibitors. X. A Reinvestigation of the Alkylation of 6-Chloropurine by 3-Bromo-1-propanol
Howard J. Schaeffer and Robert Vince
pp 710 - 712; DOI:
10.1021/jm00329a040
PDF
3′-Iodo-4-amino-4-deoxypteroylglutamic Acid (3′-Iodoaminopterin)
Ti Li Loo, Robert L. Dion, Richard H. Adamson, Michael A. Chirigos, and Roy L. Kisliuk
pp 713 - 715; DOI:
10.1021/jm00329a041
PDF
Bis(2-chloroalkyl)amides of Acylated Amino Acids. Modified Nitrogen Mustards
Irving Levi, Harold Blondal, J. William R. Weed, Alan C. Frosst, H. Christine Reilly, Franz A. Schmid, Kanematsu Sugiura, George S. Tarnowski, and C. Chester Stock
pp 715 - 718; DOI:
10.1021/jm00329a042
PDF
Chloroalkyl-N-sulfinylamines
Walter T. Smith, Wen-Yean Chen, and Myron Linfield
pp 718 - 719; DOI:
10.1021/jm00329a043
PDF
Anticholinergic Agents. Esters of 4-Dialkyl- (or 4-Polymethylene-) amino-2-butynols
Robert F. Majewski, Kenneth N. Campbell, Stanley Dykstra, Robert Covington, and Jack C. Simms
pp 719 - 720; DOI:
10.1021/jm00329a044
PDF
New Antifertility Agents. 2,3-Diphenylbenzofurans
P. K. Grover, H. P. S. Chawla, Nitya Anand, V. P. Kamboj, and Amiya B. Kar
pp 720 - 721; DOI:
10.1021/jm00329a045
PDF
5-Aryl-1,3-dihydro-2H-pyrido-1,4-diazepin-2-ones
Ruddy Littell and Duff S. Allen
pp 722 - 724; DOI:
10.1021/jm00329a046
PDF
Mammalian Antifertility Agents. II. Basic Ethers of 3,4-Diphenylcoumarins
Daniel Lednicer, Stanley C. Lyster, and Gordon W. Duncan
pp 725 - 726; DOI:
10.1021/jm00329a047
PDF
3′-Fluorofolic Acid
John A. Montgomery, Kathleen Hewson, and J. Robert Piper
pp 727 - 728; DOI:
10.1021/jm00329a048
PDF
The Synthesis of Some Benzimidazole and Oxygen Analogs of Ethyl Pteroylglutamate
Bruce I. Dittmar and Allan R. Day
pp 728 - 728; DOI:
10.1021/jm00329a049
PDF
Myelographic Agents. I. Iodobenzoates
J. E. Siggins, J. H. Ackerman, and A. A. Larsen
pp 728 - 730; DOI:
10.1021/jm00329a050
PDF
The Synthesis of Ethyl p-Nitrophenyl α-Acetoxyalkylphosphonates
L. S. Hafner, J. E. Brown, M. V. Garrison, and B. H. Alexander
pp 730 - 731; DOI:
10.1021/jm00329a051
PDF
3-Phenylphthalimidines
Price Truitt, Linda Reeves Brammer, and Linda Truitt Creagh
pp 731 - 732; DOI:
10.1021/jm00329a052
PDF
Some Compounds Derived from 1-Cyano- and 1-Bromobenzocyclobutene
Joseph A. Skorcz and Frank E. Kaminski
pp 732 - 734; DOI:
10.1021/jm00329a053
PDF
Some N-Substituted Dimethoxyphenylacetamides and Dimethoxyphenylethylamines
C. G. Stuckwisch and Janice S. Hilliard
pp 734 - 735; DOI:
10.1021/jm00329a054
PDF
Drugs of Choice 1964-1965.
John A. Owen
pp 735 - 735; DOI:
10.1021/jm00329a055
PDF
The National Formulary, Twelfth Edition.
Warren E. Weaver
pp 735 - 736; DOI:
10.1021/jm00329a056
PDF
The Quantitative Analysis of Drugs.
Anilkumar P. Parulkar
pp 736 - 736; DOI:
10.1021/jm00329a057
PDF

Issue 6


Synthesis of Potential Anticancer Agents. XXXIV. Fluorobenzimidazoles and Fluorobenzotriazoles
John A. Montgomery and Kathleen Hewson
pp 737 - 740; DOI:
10.1021/jm00330a001
PDF
2-Fluoroethylamines. II.1a Biological Evaluation and Synthesis1b
Abelardo P. Martinez, William W. Lee, and Leon Goodman
pp 741 - 744; DOI:
10.1021/jm00330a002
PDF
Potential Folic Acid Antagonists. I. The Antitumor and Folic Acid Reductase Inhibitory Properties of 6-Substituted 2,4-Diamino-5-arylazopyrimidines
J. Hampshire, P. Hebborn, A. M. Triggle, D. J. Triggle, and S. Vickers
pp 745 - 749; DOI:
10.1021/jm00330a003
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2,4-Dimethyl-5-hydroxymethylpyrimidine, a Pyridoxol Antagonist
Thomas J. Schwan, Howard Tieckelmann, James F. Holland, and Bradley Bryant
pp 750 - 753; DOI:
10.1021/jm00330a004
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The Effect of Some Sulfur-Containing Pyridine Derivatives on the Carbohydrate Metabolism of Ehrlich Ascites Tumor
D. R. Grassetti, M. E. Brokke, and J. F. Murray
pp 753 - 756; DOI:
10.1021/jm00330a005
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A Highly Reactive Sulfur Mustard Gas Derivative for Localized Infusion Studies
W. Davis and W. C. J. Ross
pp 757 - 759; DOI:
10.1021/jm00330a006
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Reactivity of Some 2-p-Nitrophenoxy-1,3,2-dioxaphospholane 2-Oxides and -dioxaphosphorinane 2-Oxides
T. R. Fukuto and R. L. Metcalf
pp 759 - 762; DOI:
10.1021/jm00330a007
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Potential Antiradiation Drugs. II.1 2-Amino-1-alkanethiols, 1-Amino-2-alkanethiols, 2-Thiazolines, and 2-Thiazoline-2-thiols2
G. Richard Handrick, Edward R. Atkinson, Felix E. Granchelli, and Robert J. Bruni
pp 762 - 766; DOI:
10.1021/jm00330a008
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Sulfamylurea Hypoglycemic Agents. I. Synthesis and Screening
J. M. McManus, J. W. McFarland, C. F. Gerber, W. M. McLamore, and G. D. Laubach
pp 766 - 776; DOI:
10.1021/jm00330a009
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Sulfamylurea Hypoglycemic Agents. II. Drug Dynamic Studies
Edward H. Wiseman, J. N. Pereira, K. F. Finger, and Rex Pinson
pp 777 - 781; DOI:
10.1021/jm00330a010
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Sulfamylurea Hypoglycemic Agents. III. Tetrasubstituted Sulfamylureas and N-Sulfamylcarbamates
J. W. McFarland, C. F. Gerber, and W. M. McLamore
pp 781 - 784; DOI:
10.1021/jm00330a011
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Sulfanilamido-s-triazines. I. Synthesis of 2-Sulfanilamido-4,6-diethyl-s-triazine and Related Compounds
W. E. Taft, H. M. Krazinski, F. C. Schaefer, and R. G. Shepherd
pp 784 - 789; DOI:
10.1021/jm00330a012
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Rifamycins. XLI.1 A New Class of Active Semisynthetic Rifamycins. N-Substituted Aminomethyl Derivatives of Rifamycin SV2
N. Maggi, V. Arioli, and P. Sensi
pp 790 - 793; DOI:
10.1021/jm00330a013
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Derivatives of 6-Aminopenicillanic Acid. VI. Synthesis of Some Derivatives of 6-Aminothiopenicillanic Acid
W. J. Gottstein, R. B. Babel, L. B. Crast, J. M. Essery, R. R. Fraser, J. C. Godfrey, C. T. Holdrege, W. F. Minor, M. E. Neubert, C. A. Panetta, and L. C. Cheney
pp 794 - 797; DOI:
10.1021/jm00330a014
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Studies on 2-(α-Hydroxybenzyl)benzimidazole (HBB) Analogs. I. Synthesis of 8-(α-Hydroxybenzyl)purines, the Diaza Analogs of HBB
William J. Haggerty, Robert H. Springer, and C. C. Cheng
pp 797 - 802; DOI:
10.1021/jm00330a015
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Substituted 5,6-Dihydro-2-(2-, 3-, and 4-pyridyl)-4H-1,3,4-oxadiazines
Donald L. Trepanier, Paul E. Krieger, and John N. Eble
pp 802 - 807; DOI:
10.1021/jm00330a016
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New Sedative and Hypotensive 3-Substituted 2,4(1H,3H)-Quinazolinediones
Shin Hayao, Herbert J. Havera, Wallace G. Strycker, T. J. Leipzig, Richard A. Kulp, and Harold E. Hartzler
pp 807 - 811; DOI:
10.1021/jm00330a017
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Unnatural Amino Acids. I. 3-Carboxytyrosine Derivatives
Frederick Leonard, Abraham Wajngurt, Walter Tschannen, and Fred B. Block
pp 812 - 815; DOI:
10.1021/jm00330a018
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Quinazolines and 1,4-Benzodiazepines. XXV.1 Structure-Activity Relationships of Aminoalkyl-Substituted 1,4-Benzodiazepin-2-ones
L. H. Sternbach, G. A. Archer, J. V. Earley, R. Ian Fryer, E. Reeder, N. Wasyliw, L. O. Randall, and R Banzger
pp 815 - 821; DOI:
10.1021/jm00330a019
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Further Syntheses in the Study of Structure-Activity Relationships of Neuropharmacologically Active Amino Acids
K. S. Cheah and J. C. Watkins
pp 821 - 824; DOI:
10.1021/jm00330a020
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Spiranes. X. Aminospiranes1,2a
Leonard M. Rice, Edward C. Dobbs, and Charles H. Grogan
pp 825 - 829; DOI:
10.1021/jm00330a021
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Structure-Activity Relationships in the Cyproheptadine Series
Edward L. Engelhardt, Howard C. Zell, Walfred S. Saari, Marcia E. Christy, C. Dylion Colton, Clement A. Stone, John M. Stavorski, Herbert C. Wenger, and Carl T. Ludden
pp 829 - 835; DOI:
10.1021/jm00330a022
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Compounds Affecting the Central Nervous System. III. Substituted 1,1-Diaryl-t-aminopropanols and Related Compounds
D. I. Barron, G. H. Hall, I. L. Natoff, H. F. Ridley, R. G. W. Spickett, and D. K. Vallance
pp 836 - 841; DOI:
10.1021/jm00330a023
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Synthesis and Cholinergic Effects of Certain N-Methoxylated Quaternary Compounds
Laszlo L. Darko, Joseph G. Cannon, John P. Long, and Thomas F. Burks
pp 841 - 844; DOI:
10.1021/jm00330a024
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Analogs of Parasympathetic Neuroeffectors. III. Synthesis and Study of Cholineselenol and Related Compounds
Wolfgang H. H. Günther and Henry G. Mautner
pp 845 - 847; DOI:
10.1021/jm00330a025
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Structure-Activity Relationship of Some New Analogs of Pethidine
D. G. Hardy, R. E. Lister, and E. S. Stern
pp 847 - 851; DOI:
10.1021/jm00330a026
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4-Substituted Piperidines. II. Reaction of 1-Benzyl-4-cyano-4-t-aminopiperidines with Organometallic Compounds
Bert Hermans, Paul Van Daele, Cornelis Van De Westeringh, Cyriel Van Der Eycken, Jozef Boey, and Paul A. J. Janssen
pp 851 - 855; DOI:
10.1021/jm00330a027
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6-Hydroxyindoles and the Metabolism of Melatonin
Robert G. Taborsky, Peter Delvigs, and Irvine H. Page
pp 855 - 858; DOI:
10.1021/jm00330a028
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In Vitro Inhibition Studies with Homogeneous Monoamine Oxidases
Alfred Burger and Sakari Nara
pp 859 - 862; DOI:
10.1021/jm00330a029
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Potential Antiradiation Agents.1a Preparation and Polymerization of Monomeric Thiazolidines1b,c
C. G. Overberger, H. Ringsdorf, and B. Avchen
pp 862 - 864; DOI:
10.1021/jm00330a030
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Substituted 2-Aminothiosulfuric Acids Derived from α-Amino Acids
Herman Gershon and Raymond Rodin
pp 864 - 866; DOI:
10.1021/jm00330a031
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2-Trifluoromethyladenosine
G. Gough and M. H. Maguire
pp 866 - 867; DOI:
10.1021/jm00330a032
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Antituberculous Compounds. XXII.1 Monoalkylaminobenzothioamides
Shichiro Kakimoto and Ikuko Tone
pp 867 - 868; DOI:
10.1021/jm00330a033
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Antituberculous Compounds. XXIII.1 Alkyl- and Acylisonicotinic Acid Hydrazides
Shichiro Kakimoto and Ikuko Tone
pp 868 - 868; DOI:
10.1021/jm00330a034
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The Use of Substituent Constants in the Correlation of Demethylation Rates
Corwin Hansch, A. Ruth Steward, and Junkichi Iwasa
pp 868 - 870; DOI:
10.1021/jm00330a035
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Alkoxyalkyltetracyclines
C. Richard Tamorria and Robert C. Esse
pp 870 - 872; DOI:
10.1021/jm00330a036
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Synthesis of Heterocyclic-Substituted Chromones and Related Compounds as Potential Anticancer Agents
Dorothy Donnelly, Rosalie Geoghegan, Conor O'Brien, Eva Philbin, and T. S. Wheeler
pp 872 - 875; DOI:
10.1021/jm00330a037
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Synthetic Spasmolytic Amines
George H. Cocolas, Souren Avakian, and Gustav J. Martin
pp 875 - 877; DOI:
10.1021/jm00330a038
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Amino Acid Analogs. I. Analogs of the Glutamic Acid-Proline Interconversion. III. Substituted 2-Acetamido-4-benzoylbutyric Acids and 5-Phenylprolines
Herman Gershon, Alfred Scala, and Raulo Parmegiani
pp 877 - 881; DOI:
10.1021/jm00330a039
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Reduction of Steroidal Enamines with Potassium Borohydride
Arvin P. Shroff
pp 881 - 883; DOI:
10.1021/jm00330a040
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Some 3,4,5-Trimethoxyphenyl Analogs of Anticonvulsants
Vasant S. Palkar and Pierre F. Smith
pp 883 - 884; DOI:
10.1021/jm00330a041
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Synthesis of Some Hydroxylamine Derivatives of Pyrimidines and Purines
Pauline K. Chang
pp 884 - 884; DOI:
10.1021/jm00330a042
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Quinoxaline Sulfonamides
S. H. Dandegaonker and C. K. Mesta
pp 884 - 886; DOI:
10.1021/jm00330a043
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Transformation Products of 5H-Dibenzo-[αd]-10,11-dihydrocyclohepten-5-one
H. L. Slates and N. L. Wendler
pp 886 - 886; DOI:
10.1021/jm00330a044
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The Synthesis of Aryloxyureas
Victor J. Bauer and Harry P. Dalalian
pp 886 - 887; DOI:
10.1021/jm00330a045
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1-Acyl-1-alkoxy-3-(p-tolylsulfonyl)ureas
James H. Cooley and J. Dana McCown
pp 887 - 888; DOI:
10.1021/jm00330a046
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Monothiophenyl Malonate
John C. Howard, Michael C. Lin, Patricia Matthews, and Sam A. Singal
pp 888 - 888; DOI:
10.1021/jm00330a047
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The Reaction of Chloramine with Mercaptopyridine and Mercaptopyrimidine Derivatives
Thomas J. Hurley and Martin A. Robinson
pp 888 - 889; DOI:
10.1021/jm00330a048
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Potential Inhibitors of Cancerous Growth. V. Substituted Benzylidene Derivatives of D-Ribose as Synthetic Intermediates
W. J. Serfontein, G. J. Lourens, and H. L. De Waal
pp 889 - 891; DOI:
10.1021/jm00330a049
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Some New Arylphosphonic and Diarylphosphinic Acids
Leon D. Freedman and G. O. Doak
pp 891 - 892; DOI:
10.1021/jm00330a050
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Substituted 1,4-Diazepin-2-ones
Ruddy Littell and Duff S. Allen
pp 892 - 893; DOI:
10.1021/jm00330a051
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Book Review - Screening Methods in Pharmacology.
Alfred Burger
pp 894 - 894; DOI:
10.1021/jm00330a052
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Addtions and Corrections - Some 2-Substituted Aminopurines and Purine Analogs.
R. M. Cresswell, T. Strauss, and George Bosworth Brown
pp 894 - 895; DOI:
10.1021/jm00330a053
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Additions and Corrections - Derivatives of Fluorenes. XVIII. New Halogenofluorenes. I. Potential Antitumor Agents.
Hsi-Lung Pan, and T. Lloyd Fletcher
pp 894 - 894; DOI:
10.1021/jm00330a600
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Additions and Corrections - 4-Substituted Piperidines. I. Derivativesof 4-t-Aminopiperidinecarboxamines.
C. van de Westeringh, P. Van Daele, B. Hermans, C. Van der Eycken, J. Boey, and P. A. J. Janssen
pp 894 - 894; DOI:
10.1021/jm00330a601
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Additions and Corrections - Structure Studies on Vancomycin.
Frederick J. Marshall
pp 894 - 894; DOI:
10.1021/jm00330a602
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Additions and Corrections - Synthesis and Biological Evaluation of Water-Soluble 2-Boronoethylthio Compounds.
D. S. Matteson, A. H. Soloway, D. W. Tomlinson, J. D. Campbell, and G. A. Nixon
pp 894 - 894; DOI:
10.1021/jm00330a603
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Additions and Corrections - 17α-Methandrostane-3α,17β-diol
K. R. Bharucha, and F. M. Martin
pp 895 - 895; DOI:
10.1021/jm00330a604
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Additions and Corrections - Hydroxy-, Nitro-, Amino-, and Methoxy-4-(4-dimethylaminostyryl)-quinolines.
C. T. Bahner, D. Brotherton, W. H. Chapman, Jr., W. Longmire, H. B. Orr, L. M. Rives, E. B. Senter, and W. Yee
pp 895 - 895; DOI:
10.1021/jm00330a605
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Additions and Corrections - Review of "Advances in Drug Research"
Alfred Burger
pp 895 - 895; DOI:
10.1021/jm00330a606
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Additions and Corrections - Phosphorylated Benzenesulfonamides as Animal Systemic Insecticides
F. A. Wagner, Jr., R. W. Baer, and G. Berkelhammer
pp 895 - 895; DOI:
10.1021/jm00330a607
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Additions and Corrections - Adrenergic Blocking Agents Derived from 1,4-Benzodiozan.
J. Augstein, S. M. Green, A. M. Munro, G. W. H. Potter, C. R. Worthing, and T. L. Wrigley
pp 895 - 895; DOI:
10.1021/jm00330a608
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